Redness and pain on the inner side of the vaginal opening need to be medicated according to the disease, for example, vaginitis can be used with metronidazole tablets and so on, urinary tract infection can be used with moxifloxacin hydrochloride tablets and so on. 1. Vaginitis: may be fungal, bacterial infection caused by the mucosa of the vagina, submucosal connective tissue inflammation. Patients may have vaginal burning pain, itching, redness and swelling and other symptoms, can be treated with cefaclor capsules, fluconazole tablets, metronidazole tablets and other drugs under the guidance of the doctor, and with potassium permanganate to carry out local cleaning. 2. Urinary tract infection: the symptoms of redness and pain on the inside of the vaginal opening may be caused by urinary tract infection, which can be treated with anti-inflammatory drugs such as moxifloxacin hydrochloride tablets and levofloxacin hydrochloride tablets under the guidance of a doctor. Redness and pain on the inside of the vaginal opening may be caused by other reasons, it is recommended that the patient go to a regular hospital as soon as possible, under the guidance of the doctor for treatment, do not blindly use medication at will.