At the age of 77, advanced colon cancer with lung metastasis can improve the prognosis of the disease and prolong the survival time of patients through chemotherapy if the body can tolerate it, and it is recommended to standardize the use of chemotherapeutic drugs under the guidance of doctors. The chemotherapeutic drugs that can be chosen for colon cancer with lung metastasis include fluorouracil, methotrexate, paclitaxel, cyclophosphamide, cisplatin, cytarabine and so on. These chemotherapeutic drugs can, to a certain extent, kill tumor cells, shrink tumor foci and inhibit tumor growth, so as to improve the prognosis of the disease. However, during the use of chemotherapeutic drugs, anemia, diarrhea, dizziness, pathological fracture and other adverse reactions, so it is necessary to use in strict compliance with the medical advice, the emergence of adverse reactions is recommended to seek medical treatment, patients allergic to the drug is prohibited.