The blisters on the hands are small and it is not recommended to break them. If the blister is large, the blister fluid can be extracted with a sterile needle to ensure the integrity of the blister wall and avoid infection. After the skin is subjected to high temperature, the permeability of local tissues increases and fluid accumulation can form blisters. If the blister is small, it is not recommended to pick it. Over time, burns can heal on their own. If the blister is large, such as a superficial second-degree burn, it is not recommended to treat it on your own. You can go to a hospital outpatient clinic. Usually, the doctor will use a sterile syringe to draw out the fluid from the blister, keeping the wall of the blister intact. The area should also be sterilized to avoid infection of the wound. If the burns are more serious, it is recommended to go to the hospital in time and ask the doctor for standardized treatment to avoid delaying the condition.