I have always wanted to write some popularized things about tumors, but on the one hand, I am too busy with my work, and on the other hand, I am not very sure whether I can explain the related knowledge in depth. However, one thing that happened in recent days and the related questions asked by patients in the clinic for many years made me feel that I should write something, otherwise it is difficult to calm down the regret and heaviness in my heart. Two days ago, a long-time friend brought her mother’s CT films to me, which showed gallbladder occupancy, and the liver was already a large area of multiple lesions. After detailed questioning, I realized that about 1 year ago, my aunt felt poor appetite and poor digestion, and at that time, she took a CT film that showed a space-occupying lesion of the gallbladder, but the local doctors could not clarify its nature. After applying some anti-inflammatory and digestive drugs, the symptoms were relieved, and the friend and her family thought there was no problem and did not care about it. During the Spring Festival, my aunt felt bloated in the upper abdomen again, and the symptoms were relieved after taking traditional Chinese medicine. In April of this year, she remembered the space occupation on her gallbladder last year, and went to the hospital for a review of the CT, and saw that it was already an advanced malignant tumor with multiple metastases. I also learned that my aunt’s appetite has been bad for a year, poor diet, weight loss of about 10 kg. now it seems that the 1 year of wasting, poor diet, epigastric distension discomfort are the early manifestations of the tumor, but did not cause my friend to pay attention to the old people have always been considered as a bad gastrointestinal. Secondly, when the malignant tumor was suspected last year, it took 1 year to think of the review for the malignant tumor, which is too long and gives enough chance for it to develop and metastasize. If you pay attention to it 1 year ago, you can continue to do some relevant examinations to clarify the nature of the tumor; if you review it earlier, you can find out the development of the tumor earlier; if you know the early performance of the tumor ….. , perhaps early surgical resection and then postoperative adjuvant therapy. Then the result and now the advanced multiple metastases prognosis is completely different. No maybe, now friends every talk about the mother on the tears, my heart also seems to have pressed a heavy stone. Clinical so many years to see a lot of similar examples. Many people mention malignant tumors think which must have very serious symptoms, in fact, a significant portion of patients may be early poor appetite, eating bad. There may be no reason to lose weight, may be a slight dry cough, or no reason for recurrent fever, etc., did not attract enough attention. When the symptoms are serious, then go to the hospital to see multiple metastases in the late stage. In the era of high incidence of tumor nowadays, it is necessary to have enough knowledge about some early manifestations of tumor and raise alertness. Regular medical checkups can provide peace of mind without any disease, and early detection and early treatment if there is any disease. That will also avoid many similar regrets.