The manifestations of elevated urine protein include: first, after the increase of urine protein, patients will have increased urine foam when they urinate. Secondly, the increase of urine protein will lead to the decrease of plasma albumin, which will cause the decrease of colloid osmotic pressure, and the patient will have edema, generally the eyelid and lower extremities swelling is obvious, and in serious cases, it will gradually develop into generalized edema, so that the patient will have chest and ascites, and the patient will have different degrees of chest tightness, abdominal distension and other symptoms. Third, the increase of urine protein will lead to an increased risk of thromboembolism afterwards. Fourth, patients may develop acute renal failure, which is manifested by a decrease in urine output and a sudden increase in blood creatinine and urea nitrogen. Fifth, after the increase of urine protein, the urine routine and 24-hour urine protein quantitative test results will be significantly higher. However, in the case of patients with light chain disease, it may lead to the paradoxical phenomenon of less urine protein and significantly higher 24-hour urine protein quantification.