Patient: Had a serum test at the dermatology hospital last week and the results were positive for herpes type 2 igm and negative for everything else. But there are no symptoms present. Is this a confirmed diagnosis? Can it be wrong? If it is positive can it be converted to negative? The doctor said that he had prescribed some cleaning water and ointment for glansitis, but now he has stopped using it. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. Most genital herpes is caused by HSV-2, but it can also be caused by HSV-l or a mixture of both types of infection. The diagnosis of genital herpes is currently based on medical history, typical symptoms and signs, such as clusters of small blisters around the external genitalia or anus that quickly break down to form vesicles or superficial ulcers, and self-induced pain. The positive HSV2 IgM mentioned in your medical history is a viral serum antibody test. Serum medium-sized specific antibodies can be detected using ELISA or Western blotting tests and can be used to differentiate between virus types. However, because serologic testing is influenced by a variety of factors such as infection status and methodology, antibody testing is only used as clinical adjunctive diagnostic evidence for genital herpes, combined with comprehensive clinical analysis, and cannot be used alone as a basis for confirming or excluding the diagnosis. Currently, antibody testing is mostly used for epidemiological investigations and retrospective clinical analysis. In short, it can only be used as a reference, so don’t worry too much.