Taking a tablet of metformin and having a two-hour postprandial blood glucose of 11.7 mmol/L usually requires treatment. Taking metformin inhibits the output of liver glycogen and improves the body’s sensitivity to insulin, thus helping to lower postprandial blood glucose levels. If the two-hour postprandial blood glucose is 11.7 mmol/L after taking metformin, it means that the blood glucose control is not satisfactory and further blood glucose control is needed, which can adjust the treatment program to lower the postprandial blood glucose. Meanwhile, attention should be paid to strengthen dietary control, should be light diet, should not eat more greasy, sugary and salty food. In addition, appropriate aerobic exercise can help control the progress of the disease and improve the quality of life of patients, such as walking, jogging, cycling and so on. Common adverse reactions to metformin include nausea, vomiting, diarrhea, and abnormal taste. If the two-hour postprandial blood glucose is 11.7mmol/L after taking metformin, it is recommended to go to the hospital in time to find out the cause of the disease and follow the doctor’s instructions to take the drug for treatment, and it is not recommended to treat the disease on your own.