For patients with hypertension combined with nephropathy, the following categories of antihypertensive drugs can be taken: 1. diuretics can be taken, but diuretics taken for a long time and in large quantities can cause hypokalemia plasma disorders, requiring regular checks of renal function and blood ions. 2. beta-blockers, when taking beta-blockers, follow the principle of small doses and long-term use. No sudden increase or sudden decrease in dosage. 3, calcium ion channel blockers, the drugs available are nifedipine, amlodipine besylate, it is recommended to apply extended-release agents, not short-acting calcium ion channel antagonists. 4, angiotensin-converting enzyme inhibitors, also known as ACEI class drugs, this drug can effectively prevent and stabilize and delay the damage of hypertension on the kidney. 5, malignant renal small Patients with arteriosclerosis can be given the drug sodium nitroprusside intravenously if there is a rapid deterioration in renal function within a short period of time and when there is a combination of acute hypertensive crisis such as hypertensive disease.