Taking ibuprofen once a month is generally not seriously harmful, but long-term use may also have adverse effects on the gastrointestinal tract, so patients are advised to avoid using the drug when it is not necessary. Ibuprofen is an antipyretic and anti-inflammatory drug, mainly used for patients with cold and fever, dysmenorrhea and other conditions. Taking ibuprofen once a month is common in patients with more severe menstrual pain, although the interval between doses is long and usually does not have serious effects on the liver and kidneys. However, after taking the drug for a long time, the body will develop a certain degree of drug resistance, and when the dosage gradually increases, it may induce nausea and vomiting, burning sensation in the stomach, and allergic dermatitis and other adverse reactions, so patients should try to reduce the dosage and the number of doses. Patients who use ibuprofen to relieve menstrual pain can try hot water bags to relieve the symptoms, and later they can also use moxibustion, acupuncture, tui na and other traditional Chinese medicine methods to regulate the body to reduce the severity of menstrual pain. Patients who take ibuprofen once a month may also be associated with cold, joint pain, headache, etc. Patients with monthly attacks should go to the hospital as soon as possible to improve the relevant examination and remove the causative factors as soon as possible. Patients with low immunity can also increase physical exercise to strengthen their body and prevent recurrence of the disease, and minimize the amount of medication used.