The course of aspirin should be taken in the context of the primary disease. It is not recommended to suspend the medication without permission, and when used to prevent thrombosis, for example, long-term use needs to be adhered to. Aspirin is a salicylic acid derivative and can be used to relieve mild or moderate pain, such as toothache, headache, and neuralgia. In addition, aspirin can also be used for transient ischemic attacks, myocardial infarction, and artificial heart valves. If used as an antipyretic and analgesic, this drug needs to be given and can be discontinued when the patient’s fever subsides and the pain is reduced or disappears. However, aspirin, as an anti-platelet drug, needs to be given for a long time when used for the treatment of coronary heart disease, cerebral infarction and other diseases, and it is not recommended to stop taking it for a period of time to avoid affecting the treatment of the disease. In addition, if peptic ulcer or gastrointestinal bleeding is caused by long-term use of aspirin, it is recommended to stop the drug immediately and visit a hospital and give the corresponding treatment under the guidance of a doctor. In addition, patients taking aspirin for a long time should also have their blood routine and coagulation function reviewed regularly. If platelets are reduced and subcutaneous petechiae are present, aspirin should be discontinued.