Toenail thickening caused by foot fungus is a nail fungal disease caused by fungal infection, which may lead to grayish-white or ebony toenails with uneven surface, hypertrophy, deformation, and brittleness, which can be treated by topical medication, oral medication, surgery and other measures. 1. Topical medication: As the medication cannot easily penetrate the nail plate, you can first seal the nail with urea ointment to soften the glass, and then use antifungal medication, such as Amorphophallus Nail Apply, Cyclopiazide Ointment and so on. 2. Oral medication: Commonly used medications include terbinafine tablets, itraconazole capsules, fluconazole capsules and other antifungal medications. 3. Surgery: If a single toenail is present and medication is not effective, nail extraction surgery can also be considered. Nail fungus disease is recommended to go to the hospital for examination first, follow the doctor’s instructions for treatment, to avoid abusing drugs by themselves.