Usually, amitriptyline does not treat prostatitis. Amitriptyline is an antidepressant that is primarily used to treat anxious or agitated depression. Its effect is to inhibit the reuptake of 5-hydroxytryptamine and norepinephrine, with stronger inhibition of 5-hydroxytryptamine reuptake and stronger sedative and anticholinergic effects. Therefore, amitriptyline is not a treatment for prostatitis. Adverse reactions such as excessive sweating, dry mouth, blurred vision, dysuria, constipation, tremor and dizziness may occur with the use of this drug. Patients with severe heart disease, recent history of myocardial infarction attack, epilepsy, glaucoma, urinary retention, hyperthyroidism, hepatic impairment, and allergy to tricyclic drugs need to be contraindicated. In addition, patients with prostatitis are advised to go to the hospital in time to avoid delays. The use of amitriptyline needs to be taken under the guidance of a doctor and should not be used privately.