The lower side of the eyes can be swollen and painful to open may be overuse of the eyes, eye inflammation, glaucoma and other conditions, need to be analyzed. 1. Excessive eye use: prolonged eye use can cause visual fatigue, which may lead to low tear secretion, dryness, swelling and pain in the eyes and other manifestations. 2. Eye inflammation: if there are bacteria and other microbial infections, the cornea produces irritation, the eyes may appear localized congestion, which may also lead to the lower side of the swelling and pain can not open. 3. Glaucoma: If there is a glaucoma condition, the pressure inside the eye is too high, which can make the eye swollen and painful, and nausea, vomiting and other symptoms may also occur. If the symptoms of swelling and pain on the lower side of the eye continue to be unrelieved, it is recommended to go to the hospital in a timely manner, under the guidance of the doctor to clarify the cause of the disease, and to carry out targeted treatment.