Pregnant women who develop herpes simplex before delivery can be treated with topical acyclovir cream or with antiviral medications, such as acyclovir and valacyclovir. 1. Non-genital herpes simplex: Herpes simplex on the hands, feet, face and other parts of the body usually does not affect the choice of mode of delivery, and can be treated with topical acyclovir cream. 2. Herpes simplex in the genital area: it may have certain effects on the fetus, such as causing fetal growth retardation, premature birth, etc., should follow the doctor’s instructions for standardized treatment, commonly used drugs are acyclovir, vasiclovir and so on. If it is determined that there is an intrauterine infection, the pregnancy needs to be terminated promptly. Pregnant women with antenatal herpes simplex need to go to the hospital in time for treatment, in addition to preventing fetal infection and choosing an appropriate mode of delivery.