LDL 4.44mmol/L is to be assessed for the patient’s risk of cardiovascular disease; low risk requires no treatment and moderate to high risk requires oral statin therapy. The normal value of LDL is 0 to 3.37 mml/L. 4.44 mmol/L is clearly above the normal value, and whether to treat or not should be evaluated for cardiovascular disease risk factors. Common risk factors include smoking, history of early onset cardiovascular disease, and obesity. Low-risk patients can be treated with dietary control without oral medications. For intermediate to high risk patients, who are at a higher risk of developing cardiovascular disease, oral statin medication, such as Rosuvastatin, is needed to keep LDL levels at a lower level. Rosuvastatin is a cholesterol-lowering drug, which is more effective in the treatment of LDL. Adverse effects of the drug include nausea, vomiting, jaundice, myalgia, and rhabdomyolysis in a small number of patients. It is contraindicated in patients with allergy to the drug, unexplained liver enzyme elevation, and severe hepatic insufficiency. If dyslipidemia is detected, prompt medical attention is recommended.