1.Overview Spinal cord stimulation (spinalcordstimulationscs) refers to the spinal cord stimulator electrodes placed in the epidural cavity of the spinal canal in the posterior part of the spinal canal, through the electric current stimulation of the spinal cord in the posterior column of the conduction tracts and the posterior horn of the sensory neurons, so as to achieve the treatment of pain or other diseases of the purpose of a therapeutic method. Principle The electrodes in the posterior part of the epidural cavity generate an electric field to stimulate the upstream structures in the posterior part of the spinal cord: dorsal roots of spinal nerves, posterior horn neurons of the spinal cord, and thalamus tracts of the spinal cord. Epidural SCS can also induce the release of its own endogenous analgesic substances in the body to varying degrees. When low-frequency electrical stimulation increases enkephalins and endorphins in the cerebrospinal fluid of the CNS, and high-frequency stimulation increases the amount and release of potentiates in the spinal cord, thus exerting an endogenous analgesic effect. Many scholars believe (115): the main theoretical basis for the role of SCS is in line with the gate (GateControlTheoryofPain) doctrine: that is, there exists in the spinal cord to control the entrance of pain signals into the brain, low-current stimulation of the spinal cord activates the pain inhibitory nerve fibers, thus shutting down the transmission of pain information, which in turn relieves and blocks the pain sensation. Indications Chronic intractable pain: SCS is seldom used for acute pain, which is dominated by post spinal surgery pain syndrome (failedbacksurgerysydromFBSS), accounting for about 70% of all cases. 1) post spinal surgery pain syndromeFBSS 2) plexus and peripheral neuropathy 3) spinal cord injury 4) complex localized pain syndrome (CRPS)