The time of leuprolide injection usually needs to be injected continuously for 6 months, and at the same time, it must be injected once every 28 days, neither earlier nor later, so as to achieve a better therapeutic effect. If the time of intramuscular injection is abnormally changed, it is likely to lead to the early resumption of menstruation, so that adenomyosis can not be effectively treated, which will have a greater impact on women’s health. At present, it is mainly used for uterine adenomyosis and ovarian chocolate cysts. For women with uterine adenomyosis, if the symptoms of dysmenorrhea are particularly obvious, but the age is relatively young, and at the same time there are still requirements for childbearing, but the natural preparation for pregnancy for more than six months has not succeeded in getting pregnant, it can be considered that leuprolide can be injected intramuscularly first to carry out the treatment, in order to induce the gradual shrinkage of the endometrial glands of the uterine myometrium, and the success of conception can only be achieved after the discontinuance of drugs. For women who have undergone surgery for ovarian chocolate cysts, in order to prevent the recurrence of coeliac cysts, intramuscular injection of leuprolide is also required.