Exacerbation of cough and shortness of breath after taking Olopatadine may be caused by uncontrolled allergy, or it may be due to the side effects of Olopatadine. Regardless of which case it belongs to, if there is a manifestation of worsening cough and shortness of breath, you should go to the hospital in time to avoid delaying your condition. Olopatadine can be used to treat allergic diseases, and if the allergic diseases are not controlled, it can lead to the symptoms of worsening cough and shortness of breath. This symptom may be caused by edema of the throat mucosa and increased secretions, and should be treated with medications such as epinephrine, as well as tracheal intubation and assisted ventilation if necessary. Olopatadine is a histamine receptor (H1) blocker and mast cell membrane stabilizer. If the patient is allergic to olopatadine, symptoms of worsening cough and shortness of breath may also occur after taking it, and treatment is also with drugs such as epinephrine, as well as tracheal intubation and assisted ventilation. If symptoms of worsening cough and shortness of breath occur after taking olopatadine, it is recommended to seek medical attention and have a doctor dispose of them.