Eat a cephalosporin drink half a catty of white wine did not react, consider not caused disulfiram-like reaction, not necessarily all cephalosporin drugs after drinking alcohol will lead to disulfiram-like reaction. In the clinical oral cephalosporins after drinking alcohol easily induced disulfiram-like reaction patients, the reason why there is no abnormal reaction is because of the different physique, for the sensitivity of the drug is different, pay attention to drink more water to accelerate the metabolism of alcohol components in the body. Once flushing, nausea and vomiting, dyspnea and other disulfiram-like reactions, need to consult a doctor in time. Taking cephalosporin antibiotics during drinking or drinking alcohol while taking cephalosporin antibiotics may affect the role of the enzyme acetaldehyde dehydrogenase, acetaldehyde needs to be broken down by the enzyme acetaldehyde dehydrogenase to complete the metabolism of alcohol, acetaldehyde is not metabolized properly will cause symptoms of toxicity, which leads to the occurrence of bisulphuric reactions. It is recommended that patients do not take any chances and continue to observe the symptoms. If a disulfiram-like reaction occurs, immediately consult the emergency department of a regular hospital.