The appearance of bumps with pressure pain in the buttock groove may be related to folliculitis, skin boils or perianal abscesses and other etiologies. 1. Folliculitis: If there is a purulent infection of a single hair follicle on the buttocks, red papules or pustules centered on the hair follicle with tenderness may appear, which may break and crust. 2. Skin boils: If there is a deep purulent infection of the hair follicle and the surrounding tissues to form a boil, there will be a localized red, swollen, hot and painful inflammatory nodule, forming a yellowish-white pus embolus at the top, and necrotic tissues and pus and blood will be discharged after it is dislodged. 3. Perianal abscess: if the lesion appears in the rectal-anal tube around the rectum, such as the anal canal behind the anus, there is purulent infection to form an abscess, perianal throbbing pain, lesions with redness, swelling, hardness and pressure pain, there may be fluctuating sensation. Buttock groove appear with pressure pain bumps need timely medical attention, clear cause, targeted treatment.