Small blisters on the hands without itching may be caused by herpes sweat, herpes simplex and other diseases, the patient should consult a doctor in a timely manner to clarify the cause of the corresponding treatment. 1. Sweat herpes: long small blisters on the hands without itching may be caused by sweat herpes, the patient’s small water is mostly symmetrical distribution, there can be local tingling, burning sensation, can be used externally with glycerite lotion, urea and other drugs for treatment. 2. Herpes simplex: hands long small blisters without itching may also be caused by herpes simplex, this blister is mainly due to viral infection and the formation of the blisters, but there is no obvious symptoms of itching, but rather manifested as pain, soreness and other discomfort. There will also be fever, fatigue and other systemic symptoms, you should pay attention to rest, appropriate physical exercise, can use acyclovir and other drugs for treatment. The above drugs into should be used under the guidance of a doctor.