Toe pain refers to pain in the bones located in the distal phalanges of the foot. There are 28 phalanges in total, 14 in each of the right and left feet, 2 in each of the bunions and 3 in each of the remaining fingers. Toe pain can be caused by a variety of reasons, such as trauma, infection, metabolic diseases, tumors, etc. Different treatments should be taken when the cause of the disease is clearly defined, and treatment of the primary disease is required when there is a primary disease. Patients should reduce the activities of the painful parts of the feet, moderate rest, for the cause of the fracture reduction and fixation, cephalosporins such as benzoxiline sodium, cefuroxime sodium and other anti-infective, non-steroidal anti-inflammatory drugs such as ibuprofen, diclofenac and other pain relief and anti-inflammatory, surgical treatment if necessary, such as tumors, and also carry out the corresponding radiotherapy, etc.. Toe pain patients should go to the hospital in time to identify the cause of treatment to avoid further progression of the disease. The above drugs should be used under the guidance of a doctor to avoid self-medication.