The so-called fire blisters on the lips should actually refer to the occurrence of herpes simplex in the mouth and lips, which is a common inflammatory skin reaction due to herpes simplex virus infection. Patients with this condition can take oral antiviral medications and apply topical antiviral medications for relief. Drugs such as acyclovir, valacyclovir, and famciclovir are commonly chosen. Alternatively, topical application of acyclovir ointment and penciclovir ointment may be used in conjunction. Generally patients can effectively relieve the situation after a week to ten days of application. But the patient must pay attention in the future in daily life, because herpes may also recur in this situation. The actual spicy food and greasy food should be eaten as little as possible, and you must pay attention to bad habits to correct, like smoking, drinking, staying up late these behaviors should be avoided.