Whether the glomerular filtration rate can be recovered or not needs to be combined with the cause of the disease. Partial renal impairment such as acute renal failure can be recovered in general, while chronic renal failure cannot be recovered in general. Glomerular filtration rate is the ability of glomerulus to filter toxins in the body, which reflects the state of renal function to a certain extent. When the glomerular filtration rate decreases and the renal function declines to the point of not being able to compensate for it, the toxic substances in the body can not be eliminated, which will cause corresponding symptoms. The prognosis of glomerular filtration rate decrease caused by different reasons is different. Commonly, such as acute glomerulonephritis, drug-induced renal injury, obstructive nephropathy, etc., the glomerular filtration rate can be restored to normal in general after active treatment and lifting of the causative factors of renal injury. Some chronic renal impairment, such as chronic glomerulonephritis, diabetic nephropathy, etc., due to long-term chronic causative factors, glomeruli, tubules and other structures have been irreversibly altered, the glomerular filtration rate is often unable to return to normal, and can only be treated to delay the deterioration of renal function. When glomerular filtration rate decreases, it is recommended to consult a doctor in a regular hospital in time to make a clear diagnosis and standardize the treatment.