There is generally no cure for chromosomal abnormalities at an advanced age, and only preconception and pregnancy tests can be used to determine whether the fetus has chromosomal abnormalities. 1. Pre-pregnancy examination: It is generally recommended that women over 35 years of age need to undergo pre-pregnancy examination, especially genetic examination, which can be done by drawing blood to determine whether there is chromosomal abnormality in women, so as to avoid chromosomal abnormality in the fetus after pregnancy, which will require termination of the pregnancy and affect women’s physical health. 2. Pregnancy test: During pregnancy, women also need to undergo Down’s syndrome, amniocentesis and non-invasive DNA test to determine whether there is any chromosomal abnormality, and if diagnosed, they need to consider termination of pregnancy because chromosomal abnormality cannot be cured. During pregnancy, it is important to follow the doctor’s instructions and undergo regular checkups at all stages of pregnancy to ensure safety.