Phthalates are a widely used class of plasticizers and also a class of endocrine disruptors that are receiving increasing attention because of their broad exposure and multisystem toxicity. Phthalates are added to creams, lotions, nail polish, perfumes, hairsprays and other cosmetics to improve product performance. 50 endocrine disruptors were detected in 213 of 42 types of commonly used toiletries (lotions, toothpastes, shampoos, cleansers, etc.) in one study, and phthalates were detected in 45 products, nearly half of which contained DEP (metabolized by the body to produce MEP), and another The detection rate of the study ranged from 71% to 79%. Franco et al. found the highest levels of MEP, MBP and DEHP metabolites in urine, and the use of shower gel, deodorant and plastic bottled water was associated with high levels of DEHP metabolites in urine, the use of perfume was associated with high levels of MiBP, anti-aging creams were associated with high levels of MEP, MBP, and MCCP, and MEP levels were associated with the type and amount of total care products used. Feiby et al. found that the detection rate of MEP and DEHP partial metabolites (MEHHP, MECPP) was 100%, and the most abundant was phthalate as MEP. the use of perfumes, deodorants, hairsprays, shampoos, and mouthwashes was associated with high MEP content in urine, and the use of perfumes, sunscreens, and shampoos was associated with high MiBP content. Wang et al. found that the use of male shampoo was associated with high levels of MBP in semen. Our group also found that the use of various toiletries among women was associated with higher levels of various types of phthalates in follicular fluid. The use of care products has become an integral part of people’s daily life and their safety is being paid more and more attention to. The use of care products increases the risk of exposure to phthalates and other toxic and harmful substances, so excessive use in life should be avoided as much as possible.