The skull is an important protective shell for the soft tissues of the human brain, once a defect occurs it should be done as soon as possible to repair the skull, otherwise it will have an impact on the patient’s image and health, and in serious cases, it may cause the patient to lose his/her life. Cranial defects can easily cause damage to the human brain, which may result in intellectual decline and slow reaction, or in severe cases, the patient may be paralyzed or become a vegetable, etc. Therefore, it is necessary to have the surgery as soon as possible. Therefore, it is necessary to perform cranial bone repair surgery as early as possible. We use the new PEEK material to do skull repair, PEEK implant meets the strictest implant standards, its insulation, strength, hardness, elasticity, etc. are comparable to the autologous skull, and can be used with 3D printing technology to perfectly restore the anatomical structure of the skull and accurately anastomose to the defective area, which is the best choice for cranial bone repair patients. Many patients will ask the peek skull repair ten years later still need to be replaced and other issues, experts said, PEEK material has and autologous bone close to the modulus of elasticity, and trauma-induced brain injury has a better protective effect. If the patient needs to take out the PEEK material due to brain disease, it can be sterilized by high temperature and high pressure for secondary use which solves the patient’s disease and reduces the cost burden of the patient. If the patient has no brain lesions, the patient does not need to remove the material, and the material will accompany the patient for the rest of his life, without replacement.