Chief Expert of Minimally Invasive Interventional Therapy Center of Henan Provincial People’s Hospital Wang ZhenyuAuthor Introduction:Wang Zhenyu, Professor, Chief Physician, Master’s Degree Supervisor, Chairman of Minimally Invasive Tumor Therapy Committee of Henan Province, Chief Expert of Minimally Invasive Interventional Therapy Center of Henan Provincial People’s HospitalSpecialties:Minimally invasive interventional methods for the treatment of a wide variety of tumors, such as lung cancer, squamous epithelial carcinoma of the upper mediastinum, malignant thymoma, mediastinal lymphatic metastasis, hepatocellular carcinoma, Pancreatic Cancer, Small Intestine Carcinoid Cancer, Kidney Cancer, Brain Metastases, Head and Neck Tumors, etc. Cao Guangshao, Interventional Department, Henan Provincial People’s Hospital, Clinic Time: Monday, Wednesday afternoon, Tuesday all day A puncture needle, guided by CT, B ultrasound, DSA, or endoscopy and other imaging equipment, bypasses the obstacles to the tumor, and then implanted radioactive particles into the tumor for blasting, directly killing the solid tumor. At present, this seems to be a new method of treating tumors that can effectively kill cancer cells while protecting normal tissues as much as possible. When I worked in the radiology department of the First Affiliated Hospital of Zhengzhou University, I had treated and counted 126 cases of middle and advanced tumor patients who had lost their surgical timing and failed by radiotherapy and chemotherapy. In addition to the mild complications in few patients and the poor efficacy for individual larger tumors, the total recent effective rate of treatment was 89.7%. However, the difficulty here is that it is not easy to accurately put radioactive particles into the tumor, especially for solid tumors in special areas, such as those located next to the heart, large blood vessels, trachea, large nerves, intestinal tubes and other important organs, or fused with them, or located in the surroundings of other organs, or those tumors that are very deep and difficult to enter into the needle, if the operation is not done correctly, the particles can not be implanted uniformly into the tumor according to the plan, and the treatment effect will be compromised. If the operation is not done properly, the particles will not be implanted into the tumor evenly as planned, and the therapeutic effect will be greatly reduced and the complications will increase. In my opinion, it is necessary to learn from the ancient art of war, improvise and crack the problem. For example, in the case of pancreatic head, pancreatic body or pancreatic tail cancer, there are vertebral body and abdominal aorta and inferior vena cava at the back, left lobe of the liver and gastrointestinal tract at the front, hepatic hilar or gallbladder at the right side and spleen at the left side, and the puncture can not reach to the tumor site straightly. In this case, the “friendly loan method” is used. It is to pass through the safer left lobe of the liver or mesentery first, or if necessary, through the gastric sinusoids, gastric body or intestines before puncturing the pancreatic lesion and implanting particles. The technique is to pass through the other organs with one needle in place as much as possible, avoiding multiple punctures to minimize the occurrence of complications. When implanting particles, the tip of the puncture needle does not retreat to the subcutaneous area, but only to the edge of the lesion, and then change the direction of the lesion to continue implanting particles, so as to avoid multiple puncture of other organs. Through this method, cancer has been eliminated for many pancreatic cancer patients. In addition to the friendly lending method, there are also the direct attack method, the step-by-step method, the method of opening the way with water, and the method of seeing the needle. However, the current minimally invasive treatment can only eradicate some malignant tumors in the early stage and smaller size. For tumors in the middle and late stages or larger size, minimally invasive treatment can only reduce the tumor load, alleviate the pain of patients, and prolong the life of patients – it is a kind of palliative treatment taken after the other methods of treatment are ineffective rather than a radical treatment. Under the condition, the most fundamental solution is to complement the advantages of other therapeutic methods and apply them in a sequential and integrated manner.