The difference between live attenuated and inactivated vaccines lies in the fact that they are vaccines with different preparation processes. Live attenuated vaccines contain active pathogens, and are therefore highly immunogenic, and generally require only one vaccination but carry a risk of causing disease; inactivated vaccines are inactivated pathogens, and generally require multiple vaccinations and the addition of vaccine adjuvants. Live attenuated vaccines are a class of vaccines with activity that can be replicated in the human body, but the pathogenicity is reduced after several laboratory passages, and the virulence is no longer able to cause disease after vaccination, but it can stimulate the body to produce antibodies and resistance to pathogens, and generally a single inoculation can produce sufficient immunity. The disadvantage is that it is not suitable for immunodeficient patients, and there is a certain risk of infection and disease. Inactivated vaccines are vaccines in which the pathogen itself has lost its infectious activity after being treated by physical or chemical methods, and they have the components of the pathogen, so they can still be recognized as pathogens by the body after entering the human body, and produce protective antibodies. The disadvantage is that multiple vaccinations are usually required to ensure the protective effect, and adjuvants need to be added to help produce antibodies. Common live attenuated vaccines include oral polio vaccine, rubella, measles, mumps vaccine, chickenpox vaccine, etc. Common inactivated vaccines include inactivated influenza vaccine, inactivated polio vaccine and rabies vaccine. Vaccines for different pathogens are made differently according to the characteristics of the pathogens, and it is recommended that you consult your doctor for specific advice on how to choose.