The etiology of frequent migraine is still unclear, at present, it is mainly believed to be related to genetic factors, nerve cell excitability disorders, endocrine factors and so on. 1. Genetic factors: According to research findings, this disease has genetic susceptibility. People with a family history of the disease have a relatively high incidence rate. 2. Nerve cell excitability disorder: there is a class of nervous system excitability-related gene mutations related to the common type of migraine in patients. It can be seen that there is a certain relationship between the two. 3. Endocrine factors: According to research, migraine may also be related to endocrine. This disease occurs mostly in adolescent women, with attacks before and during menstruation, and the symptoms gradually decrease or even disappear after menopause. The causes of migraine are complicated, once diagnosed, one should seek medical examination as early as possible, and under the guidance of the doctor to carry out regular treatment to control the symptoms and improve the condition.