Patients with pancreatic peritonitis are mostly caused by acute necrotizing hemorrhagic pancreatitis. Due to the massive destruction of pancreatic enzymes in severe pancreatitis, which causes significant infection in the abdominal cavity, patients experience abdominal pain and even episodes of colic. For peritonitis caused by pancreatitis, after the diagnosis is clear, a dissection can also be performed, and the peritoneal incision and drainage of the pancreas should be done during the operation to fully decompress the pancreas. In the postoperative period, we should also increase anti-inflammatory efforts, applying broad-spectrum cephalosporin antibiotics, plus anti-anaerobic metronidazole, ornidazole and other drugs, the combination of measures for peritonitis caused by pancreatitis are more effective, and can make rapid recovery.