Bone marrow aspiration tests usually have no obvious painful symptoms, but there is a soreness and swelling when the bone marrow is being drawn. Bone marrow aspiration is an invasive test used to diagnose hematologic disorders, or bone marrow disorders, and is usually performed under local anesthesia. The site of the aspiration is usually chosen from the anterior superior iliac spine, posterior superior iliac spine, and sternum, which are bony body landmarks that can be palpated on the body surface. In local anesthesia, the skin is first anesthetized, and then the needle is inserted directly into the bone surface for periosteal anesthesia, after which the needle is inserted into the bone with a bone marrow puncture needle under sterile conditions through the skin, periosteum, and bone, while the bone marrow fluid is extracted with a syringe for biopsy, which can effectively determine whether there are diseases of the skeletal system, such as leukemia and myeloma, without severe pain in general.