Bleeding at two months of IVF is not normal and can be caused by pre-miscarriage, ectopic pregnancy, etc. In vitro fertilization-embryo transfer (IVF-ET) is an artificial assisted reproduction technique that needs to be operated by professionals. Generally, ultrasound examination can be performed at 4~5 weeks after embryo transfer to confirm whether it is a normal pregnancy. When there is bleeding in two months after embryo transfer, it is abnormal, which may be caused by pre-eclampsia, ectopic pregnancy, etc., and needs to be clearly diagnosed and actively treated. After IVF transplantation, we should increase diet and nutrition appropriately, avoid physical labor, prohibit coitus, and continue to give luteal support therapy as prescribed by the doctor. However, when abdominal pain, vaginal bleeding and other abnormalities occur, we should go to the hospital in a timely manner, and ultrasound, progesterone and blood HCG (human chorionic gonadotropin) tests to clarify the diagnosis and timely treatment. Clinical in vitro two-month bleeding when you need to go to the hospital in a timely manner, and follow the doctor’s advice and active treatment.