Esophageal spasm is mainly caused by esophageal dysmotility, and its main causes are inflammation of the esophagus, damage to the esophageal mucosa, stimulation of the esophagus by heat or cold, gastroesophageal reflux disease, and diseases of the vagus nerve that innervates the esophagus can cause esophageal spasm. The main clinical manifestation is paroxysmal chest pain, which is mainly located behind the sternum and may radiate to the back or both sides of the shoulder nail. When this symptom occurs, cardiovascular diseases such as angina pectoris and myocardial infarction caused by coronary artery atherosclerotic heart disease should be excluded. The esophageal pressure can be significantly increased during the attack, and peristaltic waves can be seen in the barium X-ray. The main treatment is to avoid irritating food, sticky food and raw food. Sedatives, such as diazepam and phenobarbital, can be given during an attack.