Grease grains on the face can be removed by general treatment, needle clearing and physiotherapy. Grease grains, also called milia, are of unknown etiology and may be tiny cysts formed by the retention of epithelial keratin from the ducts of hair follicles, sweat glands, and other skin accessory organs. It is mostly localized as yellowish-white, firm papules with no sensory symptoms. At present, it can be removed through general treatment, needle clearing, physical therapy and other ways. 1. General treatment: when localized fat granules appear, do not scratch the local area with your hands to avoid causing skin breakage and infection. At the same time, you should pay attention to do a good job of facial cleansing, make-up should be removed in time. 2. Needle clearing: after local skin disinfection, you can use acne needles to puncture the local skin, so as to squeeze out the contents of the lesion. 3. Physical therapy: you can follow the doctor’s instructions through the high voltage, small current of high-frequency power to burn the local tissue destruction or through the carbon dioxide laser to destroy the local lesions after gasification, so as to play a therapeutic role. For patients with grease grains on the face, they can be improved by the above ways. It is recommended that patients go to the dermatology department of regular hospitals and choose the appropriate way of active treatment under the guidance of doctors.