Needle eye is usually caused by staphylococcal infection, needle eye with hard nodules that do not go away can be relieved through physical therapy, medication, surgical treatment and other ways. 1. Physical therapy: the eye can be warmed up to accelerate blood circulation and promote the receding of the nodule. However, patients with granuloma should not use their hands to squeeze the granuloma, otherwise it will lead to aggravation of the infection. 2. Medication: Needle eye nodules can be relieved by antibiotic drugs such as gentamycin ophthalmic ointment, erythromycin ophthalmic ointment and ofloxacin ophthalmic ointment under the guidance of a doctor. If the symptoms are more serious, you can use cefuroxime, amoxicillin, azithromycin and other drugs under the guidance of the doctor for relief. 3. Surgery: The hardness of the pinhole is usually caused by an abscess, which can be incised and drained through surgical treatment under the guidance of the doctor. When the needle eye with hard knot has not disappeared, it is recommended to consult a doctor in time, under the guidance of the doctor for appropriate treatment.