Why are there so many differences in treatment outcomes when taking the same Parkinson’s disease medications? This is a question that many Parkinson’s disease patients and their families have. As we know, once Parkinson’s disease is diagnosed, patients can’t live without medication for the rest of their lives, and they take these anti-Parkinson’s drugs on a daily basis to control their symptoms and take care of themselves. Therefore, medication is very important for Parkinson’s disease patients. In addition, medications have side effects, and patients want to control their symptoms with less medication and for a longer period of time, if they want to achieve this requirement, they need to follow a reasonable treatment. The following I will first understand, taking the same Parkinson’s disease drugs, why the treatment effect is so big difference?