An atypical thyroid lesion is a pathologic test result after the patient has identified a thyroid nodule, which generally means that the lesion has an atypical cellular pattern and the lesion is at junctionality, making it impossible to determine benign or malignant. Thyroid puncture pathologic findings may include the following: 1. no follicular epithelial cells were punctured; 2. benign thyroid nodules; 3. atypical lesions with unclear pathologic findings and the possibility of malignancy; 4. suspicious thyroid follicular cells with a high chance of developing malignancy; 5. extremely malignant tumors; 6. can be clearly malignant tumor, thyroid cancer. Based on the atypical thyroid lesions and the puncture biopsy, it can be determined whether it is benign or malignant. If it is clear that it is malignant, timely treatment needs to be achieved by surgical resection.