Pressing pain on the right side of the lower ribs is considered to be related to gallbladder disease, liver disease, rib fracture, local inflammation and so on. 1. Gallbladder disease: When cholecystitis or gallbladder stone occurs, there will be distension and tingling at the lower edge of the right side of the ribcage, and the pain can be triggered by deep pressure, which may be accompanied by nausea, vomiting, fever and other symptoms. 2. Liver disease: Fatty liver can cause excessive fat accumulation in the liver or cirrhosis, the liver cells will undergo lesions, which will cause pain when pressed. 3. Rib fracture: If there is a history of trauma with pain on the right side of the rib cage, the possibility of right side rib fracture should be considered. 4. Local inflammation: local inflammation of the lower right rib can be caused by strenuous exercise or exertion and cold, which may result in intercostal neuralgia, distension and pain when pressed by hand. The right side of the lower rib pain may also be related to other causes, it is recommended to consult a doctor in time to clarify the cause, under the guidance of the doctor to standardize the treatment.