There are many ways to deal with chronic eczema on the back of the thighs, first of all, to remove the cause of the disease and improve the lifestyle, further treatment can be used as systemic therapy and local treatment. 1. Remove the cause: pay attention to whether the back of thighs have been in contact with allergenic substances, or whether there have been strong stimuli such as scratching, boiling water and soap scrubbing. 2. Improve lifestyle: live a regular life and reduce stress. Clothing as loose as possible, reduce the frequency of friction and irritation with clothing, pay attention to skin hygiene, avoid using seafood and other ingredients that can easily cause allergic reactions. 3. Systemic therapy: take antihistamines such as chlorpheniramine, phenylephrine or cetirizine, which have the effect of calming, stopping itching and reducing exudation. 4. Local treatment: apply topical oils, glycerite lotion, and glucocorticoid creams such as mometasone furoate cream to help relieve itching and protect the mucous membrane barrier. If the patient’s eczema symptoms are serious, or the symptoms continue and have not improved, should go to the hospital in a timely manner, follow the doctor’s instructions for treatment, do not self-medication.