Spinal cord cavernous disease can cause different clinical manifestations due to the different size or location of the cavity, mainly including sensory abnormalities, motor abnormalities, neurotrophic disorders, and other symptoms. 1. Sensory abnormalities. Early stage usually shows spontaneous pain in the corresponding innervated area of the spinal cord. It is common in the upper limbs, chest and back, etc., followed by segmental isolated sensory abnormalities, mainly manifested as the disappearance of pain and temperature sensation in the upper limbs and chest and back with a short blouse-like distribution, and normal tactile and deep sensation, which can be developed into a variety of sensory abnormalities below the level of the cavity in the late stage. 2. Motor abnormalities. When the cavity is enlarged, the patient may have the corresponding part of muscle atrophy, muscle weakness, muscle tremor and other manifestations. 3. Neurotrophic disorders. Spinal cord cavernous disease accompanied by upper limb extremity dystrophy or hereditary sensory radiculopathy caused by lower limb amputation. It is mainly due to local skin nutritional disorder, manifested as skin thickening, keratinization, epidermal scald, persistent ulceration, scarring and other manifestations of the skin in the area of pain sensation deficiency, and even painless necrosis and detachment of the ends of fingers or toes. 4. Charcot joint. Also known as neurogenic joints, due to the loss of local joint pain sensation, joint wear and tear, deformity, atrophy, joint enlargement and other manifestations, and movement can be obvious bone friction sound, while the patient has no pain. 5. Other symptoms. Patients can also appear as urinary obstruction, dysphagia, choking on drinking water, nausea, dizziness, balance disorders, gait instability and other manifestations. Some patients may have Horner’s sign, which is characterized by ipsilateral pupil shrinkage, small eye fissure, eyeball inversion, and absence of frontal sweat on the same side.