Parkinson’s disease is a common degenerative disease of the nervous system with tremor, rigidity and motor retardation as the main manifestations, mainly seen in middle-aged and elderly people. According to statistics, the prevalence of Parkinson’s disease in China is 1.7% among people over 65 years old, and according to this projection, there are currently more than 2 million patients with Parkinson’s disease in China. Due to the lack of a cure, as the disease progresses, patients will gradually lose their ability to move on their own and lead to various complications such as pneumonia and thrombosis. Because of the tremendous health threat posed by Parkinson’s disease, the medical community worldwide has made unprecedented efforts to research Parkinson’s disease and achieved two milestones, one being the successful research on dopamine preparations and the other being the successful development of deep brain electrical stimulation (DBS, commonly known as a brain pacemaker). When dopamine preparations were first introduced, their miraculous effects made people at the time optimistic that the bastion of Parkinson’s disease treatment had been conquered. However, with 3-5 years of clinical observation, it became clear that dopamine agents also failed to stop the progression of the disease and caused many unbearable side effects, such as gastrointestinal reactions, dyskinesia, “switching” phenomena, and hallucinations. Finding a treatment with better symptom control and longer duration has become a major issue for scientists. The success of research on deep brain electrical stimulation has solved this problem more satisfactorily. This technology is based on the traditional nucleus destruction (cytoknife), which is based on the principle of implanting a neurostimulator in the body to stimulate the relevant nucleus that controls movement in the brain and suppress abnormal nerve signals, so as to improve the symptoms and restore the ability to move freely and take care of oneself. There are three main advantages: 1. Reversible: Unlike the traditional “cytoknife”, DBS treatment is reversible and non-destructive, thus preserving the possibility of receiving more advanced treatment methods in the future. Adjustable: The parameters of stimulation can be adjusted by a device similar to a TV remote control, thus adapting to the changing condition and maintaining good symptom control at all times, with a “cure”-like effect. Safety: The procedure is minimally invasive, less traumatic, and its safety has been confirmed by a large number of cases worldwide, making it the most advanced treatment for Parkinson’s disease. In addition to Parkinson’s disease, it is also widely used in the treatment of dystonia, intractable obsessive-compulsive disorder, intractable anorexia, certain types of intractable epilepsy, vegetative awakening, and intractable neuropathic pain, opening up new hope for the treatment of many difficult and strange diseases in neurosurgery.