The peripheral blood triad of acute granulocytic leukemia is defined as an elevated white blood cell count and a progressive decrease in red blood cells as well as platelets. 1. Acute granulocytic leukemia is mainly characterized by malignant proliferation of granulocytic primitive cells, including two subtypes of granulocytic leukemia undifferentiated (M1) and granulocytic leukemia partially differentiated (M2). 2. The disease usually starts suddenly and progresses rapidly. Infections and bleeding are common and often life-threatening. In addition to changes in the number of white blood cells, red blood cells, and platelets, there are also morphological abnormalities, which are usually manifested by the presence of primitive cells and naïve cells in the peripheral blood. 3. When the peripheral blood triad appears, patients are advised to undergo comprehensive treatment and care under the guidance of doctors in a timely manner: anti-infective and symptomatic treatments can be carried out, such as blood transfusion or the use of antiemetic drugs according to the situation; adrenocorticotropic hormone, vincristine, Zoerythromycin, and other chemotherapeutic drugs should be given; bone marrow transplantation can be carried out when appropriate; bed rest is allowed as much as possible, and attention should be paid to nutrition and hygiene of the surrounding environment.