Dark spots on both sides of men’s cheeks may be caused by pigmented nevus, freckles, etc. Targeted treatments, such as surgical treatments, physical treatments, etc., need to be carried out under the guidance of doctors. 1. Pigmented nevus: a benign neoplasm composed of nevus cells, generally no treatment is needed. If it is located in the exposed part of the skin and affects the aesthetics, carbon dioxide laser and other physical treatments can be used to remove it; if there is a tendency of malignant change, or if it is a large pigmented nevus, it needs to be removed by surgical methods. 2. Freckles: manifested as light brown to dark brown spots on both cheeks. Generally, no special treatment is needed, and if necessary, the use of intense pulsed light, Q-tuned laser and other treatments can be considered for removal. There are more reasons for the appearance of dark spots on the cheeks, and it is not excluded that they are caused by other factors. It is recommended that patients go to a regular medical institution for consultation, and after the doctor clarifies the cause, give targeted treatment, and do not blindly self-medication.