1. If you have a biological flap, you will need to be anticoagulated for about six months; if you have a mechanical flap, you will need to be anticoagulated for life. During your stay in the hospital, your doctor will instruct you to take warfarin according to your clotting condition. But after discharge from the hospital, you have to learn how to take it by yourself. 2.Insufficient anticoagulation can easily lead to thrombosis and failure of prosthetic valve opening and closing, leading to sudden death; too much anticoagulation can easily lead to bleeding and serious brain hemorrhage, so you must pay attention to it. 3, home according to the amount of doctor’s instructions to take, 1 week to check the coagulation function 2 times, about 2 weeks; after 1 week 1 time, about 4 weeks; followed by half a month 1 time, about 4 times; followed by 1 month 1 time, 3 consecutive months …… gradually increase the interval of time. 4, according to the results to adjust the dosage, generally look at the INR (International Normalized Ratio), the ideal value between 1.8-2.5, if you measured the value is lower than 1.8, should be appropriate to increase the dosage of warfarin; if higher than 2.5, then correspondingly reduce the dosage of warfarin, each increase or decrease of about 1/3 ~ 1/4 capsules. Suggestions: 1. You write down the phone number of your supervising physician to keep in touch at all times. 2. Keep a pamphlet to write down the time of your blood test, the test results, and the time and dosage of warfarin adjustment, so that your supervising physician can easily and accurately guide you in your medication.