If the stinging pain of urination is caused by inflammation of the urethra, it can be treated with oral antibiotics such as levofloxacin; if the pain is caused by the presence of stones in the urethra, surgical treatments such as transurethral lithotripsy are needed if necessary. 1. Urethritis: Urethritis is the most common cause of painful urination, and routine urinalysis will reveal elevated white blood cells. Usually oral antibiotic treatment, such as levofloxacin tablets, cefradine capsules and other drugs. All of the above drugs should be applied under the guidance of a doctor. 2. Urethral stones: the presence of stones in the urethra can also cause painful urination, if the stones are relatively large need surgical treatment such as transurethral lithotripsy. There may be other reasons for men to have painful urination, patients need to consult a doctor for examination and early treatment.