When it comes to ultrasound gastroscopy, most people may feel unfamiliar with it. In order to let more patients know the device, it is briefly introduced as follows, hoping that it will be helpful for consultation and treatment. Ultrasonic gastroscopy was developed in the mid to late 80’s. It has the dual function of endoscopy and ultrasound examination, and is a targeted ultrasound examination of suspected lesions in the digestive tract under the surveillance of a gastroscope. Specifically, the ultrasonic probe of different frequencies is installed on the front end of the electronic gastroscope, and when the endoscope enters the body cavity, the luminal morphology is directly observed through the endoscope, while real-time ultrasonic scanning can be performed to obtain the histological characteristics of the duct wall level and the ultrasonic images of the surrounding adjacent organs, so as to further improve the diagnosis and treatment level of endoscopy and ultrasound, which can discover the gastrointestinal, hepatobiliary and pancreatic that cannot be found by conventional ultrasound and CT It has the advantages of non-invasive, less painful and accurate diagnosis. Ren Hongyu, Department of Gastroenterology, Wuhan Union Medical College Hospital 1. Ultrasonic gastroscopy for diagnosis of early gastric cancer and prognosis of gastric cancer by adjuvant examination At present, gastric cancer is still the malignant tumor with the highest morbidity and mortality rate in most regions of China, however, like most tumors, it is difficult to achieve early detection and early diagnosis, the main reason being that patients do not have obvious abnormal sensation in early stage, and when more typical symptoms appear, it is often not early stage, and complete cure is lost. However, like most tumors, it is difficult to achieve early detection and early diagnosis. Most patients mainly have some symptoms of common gastrointestinal diseases, especially those similar to general gastritis, such as: epigastric pain, feeling of fullness, often accompanied by warmth and nausea; anorexia, and some patients may also have black stools in the early stage. These are due to the destruction of gastric mucosa by lesions. The above mild symptoms are often mistaken for chronic gastritis and fail to attract patients’ attention, therefore, people who suddenly develop the above symptoms at the age of 40 or above should seek medical consultation. For patients who have developed gastric cancer, their prognosis mainly depends on the depth of infiltration of the cancer into the stomach wall and the extent of lymph node metastasis. Ultrasonic gastroscopy can not only observe the microscopic lesions on the surface of esophagus and gastrointestinal mucosa very clearly, but also perform ultrasonic scanning, which has outstanding superiority in determining the depth of infiltration of lesions, i.e., it can further examine the lesions at all levels of the gastric wall and the lesions in the adjacent tissues and organs of the upper gastrointestinal tract, including the size and nature of lesions and the metastasis of surrounding lymph nodes, so it is especially suitable for the diagnosis of early gastric cancer and guiding the endoscopic treatment of early gastric cancer. Therefore, it is especially suitable for the diagnosis of early gastric cancer and guiding the endoscopic treatment of early gastric cancer. Therefore, ultrasound gastroscopy can improve the diagnosis rate of early gastric cancer and guide the resection of early gastric cancer through gastroscopy. At present, the five-year survival rate of patients with one-time endoscopic resection of early gastric cancer has reached more than 85%. It is especially suitable for patients of advanced age and poor general condition who can hardly afford open surgery. The preoperative estimation and selection of appropriate surgical methods for progressive gastric and esophageal cancers are the common concern of clinicians, patients and their families. Ultrasound gastroscopy has this function, which is very helpful for the staging of TNM (i.e., determination of the malignancy of the primary tumor) of upper gastrointestinal tract malignancies, the selection of surgical approach, and the estimation of postoperative prognosis. The rate of compliance with the results of surgical exploration is around 80%. 2. Detection of complex gallbladder and pancreatic lesions The detection rate of common body surface ultrasound is high for gallbladder lesions. However, because of its low frequency and interfering factors such as intestinal gas, it does not show well the lesions of the gallbladder wall and the level of the gallbladder wall. In contrast, ultrasound gastroscopy can show the gallbladder wall and its contents after entering the duodenal bulb because the probe is adjacent to the gallbladder. Therefore, ultrasound gastroscopy can help to diagnose gallbladder lesions by observing the relationship between the lesion and the gallbladder wall in some cases of suspected gallbladder malignancy or suspected gallbladder wall lesions. The early diagnosis of pancreatic cancer is still quite difficult, and most of the pancreatic cancers found clinically are advanced cases with very poor surgical results. Ultrasound gastroscopy has a 100% compliance rate for the diagnosis of tumors less than 2 cm in diameter, and the smallest lesion found is only 1 cm in diameter, which is higher than the compliance rate of cholangiography and CT. Importantly, ultrasound gastroscopy can also provide pathological diagnosis by performing puncture biopsy of occupying pancreatic lesions under direct vision. In addition, ultrasound gastroscopy can determine the healing and recurrence of peptic ulcers, determine duodenal jugular tumors, determine the extent of esophageal varices and the effectiveness of embolization therapy, and show mediastinal lesions. A general understanding of ultrasound gastroscopy shows its unique diagnostic effect on digestive system diseases. (Associate Professor Ren Hongyu, Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology)