Vulvar cancer with inguinal metastasis usually cannot be cured, but after treatment, it can improve patients’ quality of life and prolong their life span. Vulvar cancer is a relatively rare malignant tumor of the female reproductive system, especially in postmenopausal women. The main pathological type is squamous epithelial cell carcinoma, and the incidence rate increases with age. The cause of the disease is still unclear, and it may be related to human papillomavirus infection and sexually transmitted diseases. For vulvar cancer disease, if inguinal metastasis has occurred, it usually cannot be completely cured, but patients should also cooperate with doctors as soon as possible to treat the disease, and improve the prognosis of patients through surgery, radiotherapy, chemotherapy and other adjuvant treatments. Vulvar cancer patients need to build up confidence in overcoming cancer, actively cooperate with doctors in treatment, and at the same time, have regular follow-up and review to know their own situation.