Acne on the face in the 50s may be caused by insect bite dermatitis, rosacea, folliculitis, seborrheic keratosis and so on, and the patient should consult a doctor in time to clarify the cause of the disease. 1. insect bite dermatitis: if a person around 50 years old has acne on the face in summer, and has been to the woods and other places before the onset of the disease, then it should be considered to be caused by mosquito bites, which can be treated by using glycerite lotion and, if necessary, taking oral loratadine. 2. Rosacea: Formerly known as rosacea, it is a chronic inflammatory skin disease that develops in the middle of the face and is characterized by persistent erythema and capillary dilatation. The basic clinical types include erythematous capillary dilatation type, papular pustular type, nasal superfluous type and eye type, etc. Men in their 50s will have acne on their face, and they need to take oral doxycycline, minocycline, isotretinoin and other treatments. 2. Folliculitis: 50s face acne may also be caused by Staphylococcus aureus and other infected hair follicles caused by folliculitis, which may be at the top of the pimple and white pustules, the patient should do a good job of facial cleansing, and can be treated with topical fusidic acid cream. 3. Seborrheic keratosis: acne on the face in the 50s may also be caused by seborrheic keratosis due to skin aging, also known as age spots, is a benign epidermal tumor, which can be treated by laser, freezing and other methods. All of the above medications and operations should be carried out under the guidance of a doctor.