Perianal granulation 3 to choose the treatment method according to the type of disease, for example, perianal granulation due to condyloma acuminatum should be antiviral treatment, and anal papilla hypertrophy can be resected and treated. 1. Anal papilla hypertrophy: inflammation is the most common cause of anal papilla hypertrophy, and the most common manifestation of anal papilla hypertrophy is perianal granulation. Anal papilla hypertrophy is a benign lesion and can be treated conservatively without other symptoms, such as sitz baths, or surgically removed. 2. External port of anal fistula: the external port of anal fistula will be manifested as a granulation-like protrusion, in addition to the anal fistula will be manifested as a continuous flow of pus, odor, itching, pain and so on. The main treatment is surgical treatment. 3. warts: warts infection will also be manifested as perianal granulation, the main treatment is surgical excision, because the disease is due to viral infection, but also anti-viral treatment, can use such as acyclovir cream and other drugs. Perianal granulation 3 to seek medical attention in a timely manner, by a professional doctor to diagnose and treat the disease, to avoid causing delays in the condition.